HR 350z troubles

Bought my MPVI3 to tune my 01 Silverado and ended up finding out it was compatible with my 350z. I've done countless hours of research on GM tuning but I can't seem to grasp the tuning for my Nissan that has very little info on.

I feel very lost with this. I can't seem to change anything that will affect my lambda/AFR readings (very lean at full throttle and lower RPM's: 2500-4000)

I've only disabled immobilizer (08 ecu in an 07 vehicle) and adjusted fuel compensation table in the areas that are lean. I feel like this is not what I need to be looking at and adjusting.

Can anyone point me in the right direction of where to start-over?