1) If FTDI A,B are seen and not HP Tuners MPVI Channel A, B, right click on FTDI A and uninstall. Do the same for FTDI B.
2) Unplug the MPVI.
3) Unzip the USB driver files (if you downloaded them).
4) Plug the MPVI back in.
5) This time when Windows finds a new device, manually select the drivers in in the unzipped folder or CD. When all is said and done, the USB device needs to report "HP Tuners MPVI Channel A" and "HP Tuners MPVI Channel B". If not the driver have not loaded properly.
If Windows refuses to load the correct drivers, repeat step 1 but this time do not unplug the MPVI.. Right click on whatever windows installed for the MPVI and select "Update Driver". Now point Windows to the folder where the drivers are.